Network-Based Drug Repositioning

Experimental drug development is expensive, labor-intensive, and time-consuming and mostly limited to a smaller number of targets. Current studies reveal that drug repurposing acts more efficiently than de novo experimental approaches as it involves higher costs and risk. Network analysis is a multifaceted platform for drug purposing, as model interactions are constructed from different biological… Continue reading Network-Based Drug Repositioning

Drug Repurposing –A Computational Perspective

“The most fruitful basis for the discovery of a new drug is to start with an old drug”: James Black (Nobel Laureate pharmacologist) Drug repurposing (also known as drug repositioning, drug redirecting and drug re-tasking) represents the investigation of existing drugs for novel disease therapeutic. The existing drugs could be from any of the stages… Continue reading Drug Repurposing –A Computational Perspective